Cerebrospinal fluid (C.S.F.)

Cerebrospinal fluid (C.S.F.)

Defination – Modified Serous fluid
Location –
1. Ventricles of the brain
2. Central canal of the spinal cord
3. Sub Arachnoid space

• Formation – Antirior & posterior Choroid Plexus of Lateral ventricle 3th & 4th. 
• Absorption – CSF is Absorbed through the Arachnoid villi. 
• Colour – Clear as water
• Normal Value – 150 ml.
• Daily production – 500 ml
• CSF Pressure = 50 – 150 mm of water.
• S.G. of CSF = 1004 – 1005
• pH – 7.34
• Glucose in CSF – 40 – 70 mg/dl
• Protein in CSF – 15 – 50 mg/dl
• Albumin in CSF – 6.6 – 44 mg/dl
• Chloride in CSF – 720 – 750 mg/dl
• RBC cell in in CSF – Absent.
• Leucocytes – In Alults – 0 – 5 mononuclear cells/ cu mm. 
• For CSF examination Lumbar puncture is done in between L3 and L4 vertibra